Charlson Comorbidity Index (age-adjusted) = sum of age group points and comorbidity points.

Domain	Criteria	Points
Age	<50 years	0
	50-59 years	1
	60-69 years	2
	70-79 years	3
	≥80 years	4
Comorbidities (1 point each)	Myocardial infarction, congestive heart failure, peripheral vascular disease, cerebrovascular disease (without counting hemiplegia twice), dementia, chronic pulmonary disease, connective tissue disease, peptic ulcer disease, mild liver disease, diabetes without end-organ damage	+1 each
Comorbidities (2 points each)	Diabetes with end-organ damage, hemiplegia or paraplegia, moderate-severe chronic kidney disease, any solid tumour without metastases, leukaemia, lymphoma	+2 each
Comorbidities (3 points)	Moderate-severe liver disease	+3
Comorbidities (6 points each)	Metastatic solid tumour, AIDS	+6 each
Total score	CCI = sum of all applicable age and comorbidity points	0+
Approximate 10-year survival bands	CCI 0 ≈98%. 1-2 ≈90-96%. 3-4 ≈77-87%. ≥5 ≤53%	—

Age-Adjusted Charlson Comorbidity Index (CCI)